Norb and Dag both think they are home alone and invaded by aliens and monster pests.
- It's revealed that El Grapadura has his own TV show, The Loco Misadventures of Sheriff El Grapadura.
- Norb mentions writer, songwriter, and Bing's voice actor Victor Wilson.
- This episode, along with Slap Happy, is the first episode to premiere in the 2000's.
- When Daggett enters the closet, he is still half hairless, burned, and bandaged. However, when he's in the closet, he is back to his normal self.
- Before, when Dag is still injured, he switches the TV channels. When his arm is shown holding the remote, his fur is back to his normal brown color, then back to burnt.
- On the overhead shot when Norbert speaks the faded star vermin's name, his nose is miscolored to red.
- A similar red variation to his early design shown in the pilot, "Snowbound".
- Home Alone - The episode title is a reference to the 1990 family comedy film.
The image gallery for Home Loners may be viewed here.